Amy Nicholson

Host (Chapter 1: 'Wind') (voice)

Rodney Ascher

Host (Chapter 2: 'Membranes') (voice)

John Waters

Host (Chapter 3: 'Kindred') (voice)

Karyn Kusama

Host (Chapter 4: 'Multitudes') (voice)

Justin Benson

Host (Chapter 5: 'Judy') (voice)

Aaron Moorhead

Host (Chapter 5: 'Judy') (voice)

David Lowery

Host (Chapter 6: 'Dig') (voice)

David Lynch

self (archival footage)

Nicolas Cage

Sailor Ripley [archival]

Clint Eastwood

Self (archive footage)

Dennis Hopper

Self (archive footage)

Christopher Reeve

Self (archive footage)

Joaquin Phoenix

Self (archive footage)

Judy Garland

Self (archive footage)

James Stewart

Self (archive footage)

Donna Reed

Self (archive footage)

Margaret Hamilton

Self (archive footage)

Mark Hamill

Self (archive footage)

George Clooney

Self (archive footage)

Tim Blake

Self (archive footage)

Marlon Brando

Self (archive footage)