Asia Argento

Sarah

Jimmy Bennett

Young Jeremiah

Jeremy Renner

Emerson

Winona Ryder

Psychologist

Ornella Muti

Grandmother

Peter Fonda

Grandfather

Dylan Sprouse

Older Jeremiah

Kara Kemp

Social Worker #1

Cole Sprouse

Older Jeremiah

Kip Pardue

Luther

Ben Foster

Fleshy Boy

Matt Schulze

Kenny

Michael Pitt

Buddy

Brent Almond

Cop #1

David Dwyer

Cop #2

David Brian Alley

Doctor (as David Alley)

Marilyn Manson

Jackson

Lydia Lunch

Social Worker #2

Tim Armstrong

Stinky

John Robinson

Aaron

Jeremy Sisto

Chester

Russell Durham Comegys

Piggly Wiggly Clerk (as Russ Comegys)

Hasil Adkins

Street Musician

Lisa Stooksbury

Woman in Black

Katharine Franco

Nurse #2 (as Joy Ingram)

Brian Paul

EMT (uncredited)