Ron Perlman

Brother Samuel

Thomas Jane

Maj. 'Mitch' Hunter

Devon Aoki

Cpl. Valerie Duval

Sean Pertwee

Capt. Nathan Rooker

Benno Fürmann

Lt. Maximillian von Steiner

John Malkovich

Constantine

Anna Walton

Severian

Tom Wu

Cpl. Juba Kim Wu

Steve Toussaint

Capt. John McGuire

Luis Echegaray

Cpl. Jesus 'El Jesus' de Barrera

Shauna Macdonald

Adelaide

Roger Ashton-Griffiths

Science Monk

Christopher Adamson

Hodge

Jacqueline Chan

Mishima Ambassador (as Jacqui Chan)

Nicholas Ball

Plutocrat

Georgina Berriman

Grace

Georgina Bryce

Dorothy

Richard Buddle

Soldier

Tim Daniel Clark

Lead Mutant

Vyelle Croom

Bartender

Barry McCormick

Capitol Ambassador

Scott Joseph

Corporate Guard

Farhan Khan

Principal Mutant

Andrew Mackay

Science Monk's Assistant

Tatiana Lavrentieva

Refugee (uncredited)

Albert Tang

Japanese General (uncredited)

Pras Michel

Captain Michaels