Danny DeVito

Owen Lift

Billy Crystal

Larry Donner

Kim Greist

Beth Ryan

Anne Ramsey

Mrs. Lift

Kate Mulgrew

Margaret Donner

Branford Marsalis

Lester

Rob Reiner

Joel

Bruce Kirby

Detective DeBenedetto

Joey DePinto

Sergeant

Annie Ross

Mrs. Hazeltine

Raye Birk

Pinsky

Oprah Winfrey

Herself

Olivia Brown

Ms. Gladstone

Philip Perlman

Mr. Perlman

Stu Silver

Ramon

J. Alan Thomas

Millington

Randall Miller

Bucky

Andre Rosey Brown

Rosey

Tony Ciccone

Mr. Lopez

William Ray Watson

Steward

Larry McCormick

Announcer

Peter Brocco

Old Man

Hettie Lynne Hurtes

Reporter

Karen J. Westerfield

Laughing Woman

Stanley L. Gonsales

Cab Driver

Fred Gephart

Priest

Don Burns

Radio DJ (voice)

Ralph Penland

Jazz Band

Tony Dumas

Jazz Band

Ne Kaholokula

Hawaiian Band of Musicians & Dancers

Jules Dean

Student (uncredited)

Kelly Gallant

Literary Student (uncredited)

Paul McMichael

Young Teen Outside Laundromat (uncredited)

Anne Randa

Student (uncredited)