Meg Ryan

Eve Mozell Marks

Diane Keaton

Georgia Mozell

Lisa Kudrow

Maddy Mozell

Walter Matthau

Lou Mozell

Adam Arkin

Joe Marks

Jesse James

Jesse Marks

Shaun Duke

Dr. Omar Kunundar

Ann Bortolotti

Ogmed Kunundar

Cloris Leachman

Pat Mozell

Maree Cheatham

Angie

Myndy Crist

Dr. Kelly

Edie McClurg

Esther

Tracee Ellis Ross

Kim

Libby Hudson

Georgia's Assistant (Libby)

Celia Weston

Madge Turner

Stephanie Ittleson

Victoria

Charles Matthau

Young Lou

Paige Wolfe

Six-Year-Old Eve

Katie Stratton

Twelve-Year-Old Georgia

Talia-Lynn Prairie

Four-Year-Old Maddy

Ethan Dampf

Four-Year-Old Jesse Marks

Bob Kirsh

Nixon Library Representative

Kristina Dorn

Young Pat

Venessia Valentino

Nurse at Mesh Window

R.A. Buck

Gay Man

Phil Levesque

Gay Man

Mary Beth Pape

Mother at Party

Catherine Paolone

Doctor

Carol Mansell

Woman Who Recognizes Maddy

Lucky Vanous

Montana Dude

Bill Robinson

Doctor on Soap

Jaffe Cohen

Sub-Editor

Johnathan Cale

Hairdresser

Janet Dey

Event Attendee (uncredited)